About cPath
cPath is a database and software suite for storing, visualizing, and analyzing biological pathways.
Main features:
- Import pipeline capable of aggregrating pathway and interaction data sets from multiple sources, including: MINT, IntAct, HPRD, DIP, BioCyc, KEGG, PUMA2 and Reactome.
- Import/Export support for the Proteomics Standards Initiative Molecular Interaction (PSI-MI) and the Biological Pathways Exchange (BioPAX) XML formats.
- Data visualization and analysis via Cytoscape.
- Simple HTTP URL based XML web service.
- Complete software is freely available for local install. Easy to install and administer.
- Partly funded by the U.S. National Cancer Institute, via the Cancer Biomedical Informatics Grid (caBIG), and aims to meet "silver-level" requirements for software interoperability and data exchange.
cPath is currently being developed by the Computational Biology Center at Memorial Sloan-Kettering Cancer Center.
About cBio @ MSKCC
The Computational Biology Center at Memorial Sloan-Kettering Cancer Center (MSKCC) pursues computational biology research projects and the development of bioinformatics resources in the areas of:
- sequence-structure analysis
- gene regulation
- molecular pathways and networks
- diagnostic and prognostic indicators
The mission of cBio is to move the theoretical methods and genome-scale data resources of computational biology into everyday laboratory practice and use, and is reflected in the organization of cBio into research and service components -- the intention being that new computational methods created through the process of scientific inquiry should be generalized and supported as open-source and shared community resources.